Friday, March 13, 2009

Adderall Adverse Reactions

Adderall, 819 Distinct Adverse Reactions

Between 2004 and 2006 the FDA MedWatch program received 963 Individual Safety Reports naming Adderall (mixed amphetamine salts) the Primary Suspect Drug for 819 distinct adverse reactions including abdominal pain, abnormal dreams, acne, acute psychosis, adrenal adenoma, affect lability, aggression, agitation, antisocial behaviour, anxiety, apathy, aphasia, apraxia, arrhythmia, arthritis, asthma and atrial fibrillation.

All 819 Adderall side effects are listed below in alphabetical order.

Abasia, Abdominal Discomfort, Abdominal Distension, Abdominal Pain, Abdominal Pain Upper, Abdominal Tenderness, Abnormal Behaviour, Abnormal Dreams, Abnormal Sensation In Eye, Abortion Induced, Accident, Accidental Drug Intake By Child, Accidental Exposure, Accidental Overdose, Acid Base Balance Abnormal, Acne, Activities of Daily Living Impaired, Acute Abdomen, Acute Coronary Syndrome, Acute Myocardial Infarction, Acute Psychosis, Acute Pulmonary Oedema, Adrenal Adenoma, Adrenal Carcinoma, Adrenal Insufficiency, Adverse Event, Affect Lability, Affective Disorder, Aggression, Agitation, Agonal Rhythm, Alanine Aminotransferase Increased, Alcohol Poisoning, Alcohol Problem, Alcohol Use, Allergy To Animal, Alopecia, Alopecia Areata, Amaurosis Fugax, Amnesia, Amniotic Fluid Volume Decreased, Anaemia, Anal Injury, Anaphylactic Reaction, Anger, Angina Pectoris, Anorexia, Anoxia, Anterograde Amnesia, Antinuclear Antibody Positive, Antisocial Behaviour, Anxiety, Aortic Dissection, Aortic Valve Disease, Aortic Valve Incompetence, Apallic Syndrome, Apathy, Aphasia, Apoptosis, Apraxia, Arrhythmia, Arrhythmogenic Right Ventricular Dysplasia, Arterial Injury, Arteriosclerosis Coronary Artery, Arteriospasm Coronary, Arthralgia, Arthritis, Aspartate Aminotransferase Increased, Asthenia, Asthma, Atherosclerosis, Atrial Fibrillation, Atrial Septal Defect, Attention Deficit Hyperactivity Disorder, Attention-Seeking Behaviour, Autonomic Nervous System Imbalance, Back Pain, Bacterial Infection, Balance Disorder, Band Neutrophil Percentage Increased, Bankruptcy, Belligerence, Benign Neoplasm, Benign Neoplasm of Eyelid, Bicuspid Aortic Valve, Bile Duct Obstruction, Binge Eating, Bipolar Disorder, Bladder Disorder, Blindness, Blindness Transient, Blister, Blood Alkaline Phosphatase Increased, Blood Aluminium Increased, Blood Bicarbonate Decreased, Blood Bicarbonate Increased, Blood Bilirubin Increased, Blood Calcium Increased, Blood Cannabinoids, Blood Creatine Increased, Blood Creatine Phosphokinase Abnormal, Blood Creatine Phosphokinase Increased, Blood Creatine Phosphokinase Mb Increased, Blood Glucose Decreased, Blood Glucose Increased, Blood PH Decreased, Blood Potassium Decreased, Blood Potassium Increased, Blood Pressure Decreased, Blood Pressure Diastolic Decreased, Blood Pressure Diastolic Increased, Blood Pressure Increased, Blood Pressure Systolic Increased, Blood Sodium Decreased, Blood Sodium Increased, Blood Urea Increased, Body Temperature Decreased, Body Temperature Increased, Bone Marrow Depression, Bone Pain, Borderline Glaucoma, Bradycardia, Bradyphrenia, Brain DEATH, Brain Herniation, Brain Hypoxia, Brain Natriuretic Peptide Increased, Brain Neoplasm, Brain Oedema, Brain Stem Haemorrhage, Brain Stem Infarction, Brain Stem Syndrome, Breast Pain, Bronchitis, Bruxism, Bundle Branch Block, Bundle Branch Block Left, Cachexia, Cardiac Arrest, Cardiac Discomfort, Cardiac Disorder, Cardiac Failure Chronic, Cardiac Failure Congestive, Cardiac Fibrillation, Cardiac Hypertrophy, Cardiac Monitoring, Cardiac Murmur, Cardiac Operation, Cardiomegaly, Cardiomyopathy, Cardio-Respiratory Arrest, Cardiotoxicity, Cardiovascular Disorder, Carotid Artery Occlusion, Central Line Infection, Central Nervous System Lesion, Central Nervous System Stimulation, Cerebellar Haemorrhage, Cerebral Haemorrhage, Cerebral Infarction, Cerebral Ischaemia, Cerebrovascular Accident, Cerebrovascular Disorder, Chemical Poisoning, Chest Discomfort, Chest Pain, Chills, Cholecystectomy, Cholecystitis Acute, Cholecystitis Infective, Cholelithiasis, Chorea, Chronic Hepatitis, Chronic Obstructive Pulmonary Disease, Circulatory Collapse, Circumstance Or Information Capable of Leading To Medication Error, Clonus, Coagulopathy, Cognitive Disorder, Cold Sweat, Colitis, Coma, Completed SUICIDE, Complex Partial Seizures, Compulsions, Concussion, Condition Aggravated, Conduction Disorder, Confusional State, Congestive Cardiomyopathy, Conjunctival Hyperaemia, Conjunctivitis, Consciousness Fluctuating, Constipation, Continuous Haemodiafiltration, Contrast Media Reaction, C-Reactive Protein Increased, Convulsion, Convulsive Threshold Lowered, Coordination Abnormal, Coronary Arterial Stent Insertion, Coronary Artery Aneurysm, Coronary Artery Disease, Coronary Artery Occlusion, Coronary Artery Perforation, Coronary Artery Thrombosis, Cough, Crohn's Disease, Crying, Crystal Urine Present, Cyanosis, Cyclothymic Disorder, Deafness Bilateral, DEATH, DEATH of Parent, Decreased Activity, Decreased Appetite, Deformity, Dehydration, Delirium, Delusion, Dementia, Dementia Alzheimer's Type, Depressed Level of Consciousness, Depressed Mood, Depression, Depression SUICIDAL, Diabetes Insipidus, Dialysis, Diarrhoea, Difficulty In Walking, Dilatation Atrial, Dilatation Ventricular, Diplopia, Discomfort, Disease Recurrence, Dislocation of Vertebra, Disorientation, Disseminated Intravascular Coagulation, Dissociation, Disturbance In Attention, Disturbance In Social Behaviour, Divorced, Dizziness, Drooling, Drowning, Drug Abuser, Drug Administration Error, Drug Dependence, Drug Dispensing Error, Drug Dose Omission, Drug Effect Decreased, Drug Effect Prolonged, Drug Exposure Before Pregnancy, Drug Exposure During Pregnancy, Drug Hypersensitivity, Drug Ineffective, Drug Interaction, Drug Level Increased, Drug Prescribing Error, Drug Screen Positive, Drug Therapy Changed, Drug Tolerance, Drug Tolerance Increased, Drug Toxicity, Drug Withdrawal Syndrome, Dry Mouth, Dysarthria, Dysgeusia, Dysgraphia, Dyskinesia, Dyspepsia, Dysphemia, Dyspnoea, Dyspnoea at Rest, Dyspnoea Exertional, Dystonia, Dysuria, Ear Infection, Eating Disorder, Economic Problem, Educational Problem, Ejection Fraction Decreased, Electrocardiogram Abnormal, Electrocardiogram Change, Electrocardiogram P Wave Abnormal, Electrocardiogram Q Wave Abnormal, Electrocardiogram Qrs Complex Prolonged, Electrocardiogram Qrs Complex Shortened, Electrocardiogram QT Corrected Interval Prolonged, Electrocardiogram QT Prolonged, Electrocardiogram St Segment Depression, Electrocardiogram St Segment Elevation, Electrocardiogram St-T Segment Elevation, Electrocardiogram T Wave Inversion, Electrocardiogram T Wave Peaked, Emotional Disorder, Emotional Distress, Encephalopathy, Endocardial Disease, Endocardial Fibroelastosis, Endocarditis, Eosinophil Count Increased, Eosinophil Percentage Increased, Eosinophilia, Epididymitis, Eructation, Erythema, Escherichia Infection, Euphoric Mood, Excitability, Exercise Capacity Decreased, Exhibitionism, Exophthalmos, Exposure To Toxic Agent, Exsanguination, Extrapyramidal Disorder, Extravasation, Eye Haemorrhage, Eye Infection, Eye Movement Disorder, Eye Pain, Eyelid Oedema, Facial Bones Fracture, Facial Palsy, Facial Spasm, Fall, Family Stress, Fatigue, Fear, Feeling Abnormal, Feeling Cold, Feeling Drunk, Feeling Guilty, Feeling Hot, Fight In School, Finger Amputation, Flashback, Flat Affect, Flushing, Foetal Growth Retardation, Food Interaction, Foreign Body Trauma, Fungal Infection, Gallbladder Disorder, Gallop Rhythm Present, Gangrene, Gastroenteritis, Gastroenteritis Viral, General Physical Health Deterioration, Genital Infection Bacterial, Genital Pain Male, Glaucoma, Glossodynia, Grand Mal Convulsion, Grandiosity, Growing Pains, Growth Retardation, Haematocrit Increased, Haematotoxicity, Haematuria, Haemodialysis, Haemoglobin Increased, Haemoptysis, Haemorrhage, Hair Plucking, Hairy Cell Leukaemia, Halitosis, Hallucination, Hallucination (Auditory), Hallucination (Tactile), Hallucination (Visual), Hallucinations (Mixed), Head Injury, Headache, Heart Rate Decreased, Heart Rate Increased, Heart Rate Irregular, Heat Stroke, Hemianopia, Hemiparesis, Hepatic Atrophy, Hepatic Congestion, Hepatic Cyst, Hepatic Failure, Hepatic Function Abnormal, Hepatic Steatosis, Hepatitis, Hepatitis C, Hepatocellular Damage, Herpes Zoster, Homicidal Ideation, HOMICIDE, Hostility, Hot Flush, Hydronephrosis, Hyperaesthesia, Hyperhidrosis, Hyperkalaemia, Hypermetropia, Hyperreflexia, Hypersensitivity, Hypersomnia, Hypertension, Hyperthermia, Hyperthermia Malignant, Hypertrophic Cardiomyopathy, Hyperventilation, Hypoaesthesia, Hypoaesthesia Oral, Hypoglycaemia, Hypoglycaemic Coma, Hypokinesia, Hypomania, Hyponatraemia, Hypotension, Hypothermia, Hypotonia, Hypotrichosis, Hypoxia, Ill-Defined Disorder, Impaired Driving Ability, Impaired Self-Care, Impaired Work Ability, Impatience, Imprisonment, Impulse-Control Disorder, Impulsive Behaviour, Inappropriate Affect, Incoherent, Incontinence, Incorrect Dose Administered, Incorrect Route of Drug Administration, Infection, Inflammation, Influenza, Influenza Like Illness, Initial Insomnia, Injury, Injury Asphyxiation, Insomnia, Intentional Drug Misuse, Intentional Misuse, Intentional Overdose, Intentional Self-Injury, International Normalised Ratio Increased, Intestinal Functional Disorder, Intestinal Infarction, Intracranial Aneurysm, Intraventricular Haemorrhage, Irritability, Ischaemia, Ischaemic Cerebral Infarction, Jaundice Neonatal, Job Dissatisfaction, Joint Stiffness, Kidney Infection, Laboratory Test Abnormal, Laceration, Lacrimation Increased, Lacunar Infarction, Laryngeal Oedema, Learning Disability, Left Ventricular End-Diastolic Pressure Increased, Legal Problem, Lethargy, Leukopenia, Libido Increased, Limb Discomfort, Lip Dry, Listless, Liver Disorder, Local Swelling, Logorrhoea, Loss of Consciousness, Loss of Employment, Lung Disorder, Lung Injury, Lupus-Like Syndrome, Lymphadenopathy, Maculopathy, Major Depression, Malaise, Malignant Hypertension, Malnutrition, Mania, Markedly Reduced Dietary Intake, Maternal Drugs Affecting Foetus, Medication Error, Medication Tampering, Melanocytic Naevus, Memory Impairment, Menorrhagia, Menstruation Irregular, Mental Disorder, Mental Impairment, Mental Status Changes, Mesenteric Artery Thrombosis, Metabolic Acidosis, Metabolic Disorder, Metanephrine Urine Increased, Migraine, Mitral Valve Incompetence, Mitral Valve Prolapse, Mood Altered, Mood Swings, Mouth Ulceration, Movement Disorder, Mucosal Dryness, Multi-Organ Disorder, Multi-Organ Failure, Multiple Allergies, Multiple Drug Overdose, Multiple Drug Overdose Intentional, MURDER, Muscle Spasms, Muscle Spasticity, Muscle Strain, Muscle Tightness, Muscle Twitching, Muscular Weakness, Musculoskeletal Chest Pain, Musculoskeletal Pain, Musculoskeletal Stiffness, Myalgia, Mydriasis, Myocardial Fibrosis, Myocardial Infarction, Myocardial Ischaemia, Myocarditis, Myocarditis Bacterial, Myoclonus, Myopia, Myositis, Narcolepsy, Nasopharyngitis, Nausea, Neck Injury, Neoplasm Malignant, Nephritis Interstitial, Nephrolithiasis, Nephrotic Syndrome, Nerve Conduction Studies Abnormal, Nerve Injury, Nervous System Disorder, Nervousness, Neuroleptic Malignant Syndrome, Neuron-Specific Enolase Decreased, Neurotoxicity, Neutrophil Percentage Increased, Nightmare, No Adverse Drug Effect, Noctiphobia, Nodal Rhythm, Normochromic Normocytic Anaemia, Obsessive Thoughts, Obsessive-Compulsive Disorder, Oedema, Oedema Peripheral, Off Label Use, Oppositional Defiant Disorder, Optic Nerve Cupping, Optic Neuritis, Oral Intake Reduced, Oral Mucosal Exfoliation, Oral Pain, Oral Pruritus, Orthopnoea, Orthostatic Hypotension, Overdose, Oxygen Saturation Decreased, Pain, Pain In Extremity, Pallor, Palpitations, Pancytopenia, Panic Attack, Panic Reaction, Papilloedema, Paradoxical Drug Reaction, Paraesthesia, Paraesthesia Oral, Paralysis, Paranoia, Pathogen Resistance, PCO2 Decreased, PCO2 Increased, Penile Infection, Penile Pain, Penile Swelling, Performance Status Decreased, Pericardial Effusion, Pericarditis, Peripheral Coldness, Persecutory Delusion, Personality Change, Petit Mal Epilepsy, Pharmaceutical Product Complaint, Pharmaceutical Product Counterfeit, Pharyngeal Hypoaesthesia, Pharyngeal Oedema, Pharyngitis Streptococcal, Pharyngolaryngeal Pain, Phobia, Photosensitivity Reaction, Physical Assault, Platelet Count Decreased, Platelet Count Increased, Pleural Effusion, Pneumonia, Pneumonia Mycoplasmal, Pneumothorax, Po2 Increased, Poisoning, Polysubstance Abuse, Polytraumatism, Poor Quality Drug Administered, Post Procedural Complication, Post Procedural Haemorrhage, Postnasal Drip, Post-Traumatic Stress Disorder, Posture Abnormal, Pregnancy, Prescribed Overdose, Pruritus, Psychiatric Symptom, Psychomotor Hyperactivity, Psychotic Disorder, Pulmonary Congestion, Pulmonary Haemorrhage, Pulmonary Hypertension, Pulmonary Oedema, Pulse Absent, Pupillary Light Reflex Tests Abnormal, Pupillary Reflex Impaired, Pyrexia, Rash, Rash Erythematous, Rash Generalised, Rash Macular, Rash Maculo-Papular, Rash Pruritic, Reaction To Medical Agent Preservatives, Rebound Effect, Rectal Haemorrhage, Refusal of Treatment By Patient, Refusal of Treatment By Relative, Renal Failure, Renal Failure Acute, Renal Tubular Disorder, Renal Tubular Necrosis, Repetitive Speech, Respiratory Arrest, Respiratory Depression, Respiratory Distress, Respiratory Failure, Respiratory Rate Increased, Respiratory Tract Infection, Restlessness, Resuscitation, Retinal Haemorrhage, Retinal Tear, Retinal Vein Occlusion, Retinopathy, Retrograde Amnesia, Rhabdomyolysis, Rheumatoid Arthritis, Road Traffic Accident, Rocky Mountain Spotted Fever, Salivary Duct Obstruction, Salivary Gland Enlargement, Salivary Hypersecretion, Scar, SCHIZOPHRENIA, Scleritis, Screaming, Scrotal Abscess, Scrotal Oedema, Sedation, Self Injurious Behaviour, Self Mutilation, Self-Injurious Ideation, Self-Medication, Sensation of Heaviness, Sensation of Pressure, Sensitivity of Teeth, Sensory Disturbance, Sepsis, Septic Shock, SEROTONIN SYNDROME, Sexual Dysfunction, Shock, Simple Partial Seizures, Sinus Disorder, Sinus Headache, Sinus Tachycardia, Skin Desquamation, Skin Discolouration, Skin Exfoliation, Skin Laceration, Skin Ulcer, Skull Fractured Base, Sleep Apnoea Syndrome, Sleep Disorder, Sleep Terror, Sluggishness, Small for Dates Baby, Small Intestinal Obstruction, Sneezing, Social Avoidant Behaviour, Social Problem, Somnolence, Speech Disorder, Spinal Fracture, Splenomegaly, Staphylococcal Infection, Status Epilepticus, Stevens-Johnson Syndrome, Stomach Discomfort, Stomatitis, Streptococcal Infection, Stress, Stridor, Stupor, Subarachnoid Haemorrhage, Substance Abuse, Sudden Cardiac DEATH, Sudden DEATH, Suicidal Behaviour, Suicidal Ideation, SUICIDE Attempt, Supraventricular Tachycardia, Swelling, Swelling Face, Swollen Tongue, Syncope, Syncope Vasovagal, Tachycardia, Tachypnoea, Tardive Dyskinesia, Terminal State, Tetany, Theft, Therapeutic Agent Toxicity, Therapeutic Product Ineffective, Therapeutic Response Decreased, Therapeutic Response Unexpected, Therapeutic Response Unexpected With Drug Substitution, Therapy Non-Responder, Thermal Burn, Thinking Abnormal, Thirst, Throat Irritation, Throat Tightness, Thrombocytopenia, Thrombophlebitis, Thrombosis, Tic, Tongue Disorder, Tonic Convulsion, Tonsillar Hypertrophy, Tooth Discolouration, Tooth Injury, Tourette's Disorder, Toxic Epidermal Necrolysis, Toxic Shock Syndrome, Toxic Skin Eruption, Toxicologic Test Abnormal, Trance, Transient Ischaemic Attack, Traumatic Shock, Treatment Noncompliance, Tremor, Tricuspid Valve Incompetence, Trismus, Troponin I Increased, Unintended Pregnancy, Unresponsive To Verbal Stimuli, Urethral Disorder, Urethral Fistula, Urethral Pain, Urethral Stenosis, Urinary Incontinence, Urinary Retention, Urine Flow Decreased, Urticaria, Vascular Occlusion, Vasculitis, Vasculitis Cerebral, Vasoconstriction, Venous Stasis, Venous Thrombosis, Ventricle Rupture, Ventricular Arrhythmia, Ventricular Dysfunction, Ventricular Extrasystoles, Ventricular Fibrillation, Ventricular Hypertrophy, Ventricular Hypokinesia, Ventricular Tachycardia, Verbal Abuse, Victim of Crime, Viral Infection, Viral Upper Respiratory Tract Infection, Vision Blurred, Visual Acuity Reduced, Visual Disturbance, Vitreous Floaters, Vitreous Haemorrhage, Vomiting, Weight Decreased, Weight Increased, Wheelchair User, Wheezing, White Blood Cell Count Abnormal, White Blood Cell Count Decreased, White Blood Cell Count Increased, Wolff-Parkinson-White Syndrome.

Adderall's top 20 side effects reported to MedWatch between Jan. 2004 and Dec. 2006:

Drug Abuser - 120 cases
Drug Ineffective - 106 cases
Psychotic Disorder - 51 cases
Abnormal Behaviour - 47 cases
Headache - 46 cases
Insomnia - 42 cases
Drug Toxicity - 41 cases
Agitation - 40 cases
Aggression - 39 cases
Intentional Misuse - 38 cases
Fatigue - 36 cases
Chest Pain - 35 cases
Increased Heart Rate - 34 cases
Cardiomyopathy - 33 cases
Completed Suicide - 29 cases
Depression - 29 cases
Feeling Abnormal - 29 cases
Dizziness - 28 cases
Increased Blood Pressure - 28 cases
Dyspnoea - 26 cases

Thanks to and for making the MedWatch data available to the public.